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This article contains plot details about an important, recent or upcoming episode. Read at your own risk!
Coulson is forced to team up with surprising allies to save the world, while the S.H.I.E.L.D. team attempts to track down and rescue him.
- Coming soon
- Clark Gregg as Phil Coulson
- Ming-Na Wen as Melinda May
- Chloe Bennet as Daisy 'Skye' Johnson/Quake
- Iain De Caestecker as Leo Fitz
- Elizabeth Henstridge as Jemma Simmons
- Henry Simmons as Alphonso Mackenzie
- Natalia Cordova-Buckley as Elena "Yo-Yo" Rodriguez
- Adrian Pasdar as Brigadier General Glenn Talbot
- Jeff Ward as Deke Shaw
- Catherine Dent as General Hale
- Dove Cameron as Ruby Hale
- Brian Patrick Wade as Carl Creel
- Maximilian Osinski as Agent Davis
- Spencer Treat Clark as Werner von Strucker
- Lola Glaudini as Polly Hinton
- Lexy Kolker as Robin Hinton
- Aaron Fili as scientist
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